Mesothelioma Prognosis Means What ?


Mesothelioma Prognosis Means What ?

Mesothelioma Prognosis :

A mesothelioma prognosis is what doctors describe as an overall outlook for a specific patient. Mesothelioma is an aggressive cancer with an average life expectancy of 14 to 22 months.

But it is often terminal with most patients living only 1 year after diagnosis.

A patient’s prognosis helps determine the treatment options they can pursue.

The prognosis for most mesothelioma patients is generally poor because there is no cure for this disease.

Prognosis is often measure in terms such as “good,” “favorable,” “bad” or “poor” based on how the cancer is expect to progress.

It includes the prospect of recovery and helps determine what treatment options may be available.

When patients ask about their prognosis, what they usually want to know is how long they will live.

Early-Stage Prognosis

People diagnosed early, in stage 1 or stage 2, often qualify for surgery.

which offers the best chance at long-term survival.

Approximately 20 percent of pleural mesothelioma patients are diagnose early enough to qualify for surgery.

Stage 1 patients who undergo surgery have a median life expectancy of 22.2 months.

Late-Stage Prognosis

Most patients are diagnose late, at stage 3 or 4, and do not qualify for surgery. Stage 4 patients who undergo treatment have a median life expectancy of 14.9 months.

Although statistics play a part in determining your prognosis, every mesothelioma case is unique.

Some mesothelioma patients are beating the typical outlook thanks to advances in treatment and care. Survivors credit life span increases to multimodal treatment, improvements in their diet and complementary therapies.

Prognosis by Mesothelioma Type

The type of mesothelioma, which is determine by the location.

where it first develops, has an effect on the prognosis of the disease.

Pleural mesothelioma

Pleural mesothelioma affects the lung linings and is the most common type of mesothelioma, making up 80 – 90% of all diagnoses.

Treatment is typically multimodal, and on average, pleural mesothelioma patients.

who receive some form of treatment live 12 months after diagnosis.

Peritoneal mesothelioma

Peritoneal mesothelioma affects the linings of the abdomen and is the second most common type of mesothelioma, accounting for 15 – 20% of cases.

Common treatments often involve surgery and chemotherapy. The median survival period for patients with peritoneal mesothelioma is one year.

However, patients who are healthy enough to undergo surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) have been able to improve prognosis, with a 5-year survival rate as high as 67%.

Pericardial mesothelioma

Pericardial mesothelioma is seen in the linings of the heart and is one of the rarest forms of the disease, seen in 1 – 2% of mesothelioma diagnoses.

This type has a very poor prognosis of about six months, with many cases not properly diagnose until an autopsy is perform.

With early detection, treatment is typically palliative to improve symptoms and quality of life.

Testicular Mesothelioma

Testicular mesothelioma is seen in the linings of the testes and is the rarest of the four types, seen in only 1% of all diagnosed cases.

Prognosis for testicular mesothelioma patients is typically 20 – 23 months, though some have lived much longer.

Treatment involves a multimodal approach of surgery, chemotherapy and radiation therapy.

What Factors Affect Mesothelioma Prognosis?

There are five primary factors that doctors consider when determining a prognosis for mesothelioma patients.

While these factors can help physicians provide patients with a prognosis, disease progression will still differ on a case-by-case basis.


Stage is the most important factor in determining a patient’s prognosis. Patients diagnosed at an early stage of mesothelioma will have more treatment options and a better prognosis than those diagnosed at a later stage.

The life expectancy for stage 1 patients is typically 21 months or longer, and 19 months for stage 2 patients.

By stage 3 and stage 4, patients generally only have palliative treatment options available to prolong life and improve quality of life.

On average, stage 3 patients have a life expectancy of 16 months, while stage 4 patients survive for about 12 months after diagnosis.

Cell Type

Of the three primary mesothelioma cell types, epithelioid mesothelioma is the most common and also has the best prognosis, as epithelioid cells spread less aggressively and are more responsive to treatment.

Biphasic mesothelioma has a worse prognosis due to the presence of sarcomatoid cells.

Sarcomatoid mesothelioma has the least favorable prognosis of these cell types, as these cells spread aggressively and are not as responsive to cancer treatments.

In some cases, patients may be diagnosed with other rare cell types, which have prognoses that vary from a few months to 10 years or longer.


Average life expectancy varies for patients diagnosed with pleural, peritoneal, pericardial and testicular mesothelioma.

Testicular patients have a favorable prognosis with a median survival of around 20 – 23 months.

Peritoneal patients typically survive one year or longer, and pleural mesothelioma patients have an average prognosis of about six months to one year.

Pericardial patients have the least favorable prognosis of the types, with many diagnosed posthumously.


If the mesothelioma has spread to other parts of the body from where it originated, the prognosis is much worse.

Once the disease begins to spread, it is much harder to remove the cancer through surgery or kill the cancer cells with chemotherapy.

Localized mesothelioma can be treated more aggressively with multimodal treatments and lead to a better prognosis and longer lifespan.

Overall Health

Patients who are relatively young and healthy can have a better prognosis because their bodies are better able to handle aggressive treatments.

Older patients may not be able to withstand the side effects of surgery, chemotherapy or radiation therapy, and also tend to have other conditions that can worsen the disease or limit treatment options.

In general, poor overall health will limit treatment options and lower life expectancy for patients facing a mesothelioma diagnosis.

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